Best Daily Contact Lens Comfort Products for Dryness and Cleaning
The products listed here support contact lens comfort through rewetting, cleaning, or disinfection; none is a contact lens itself. Refresh Contacts is best for soft-lens rewetting, Boston Rewetting Drops are designed for rigid gas permeable lenses, and Biotrue Hydration Plus and OPTI-FREE Replenish are multipurpose solutions for lens care. The ultrasonic cleaner is an optional cleaning device. Match each product to your lens type and follow your eye-care professional’s instructions.
| Product | Best suited for | Main role |
|---|---|---|
| Refresh Contacts Comfort Drops | Contact wearers seeking rewetting drops | Lubricates and rewets lenses while worn |
| Biotrue Hydration Plus | Wearers who want multipurpose solution | Cleans, disinfects, and conditions lenses |
| Boston Rewetting Drops | Rigid gas permeable lens wearers | Rewets and lubricates RGP lenses |
| UpaClaire Ultrasonic Cleaner | Wearers considering an extra cleaning device | Ultrasonic cleaning alongside solution |
| OPTI-FREE Replenish | Wearers seeking multipurpose solution | Cleans and disinfects lenses |
Refresh Contacts Comfort Drops

These artificial tears are made to soothe contact lens dryness and rewet lenses. The listed features say the drops lubricate and cushion lenses before application, and can also be used while contacts remain in the eyes. That makes this a practical option for people seeking on-the-go moisture rather than a cleaning or disinfecting solution.
Best for: Contact lens wearers who want drops for dryness during the day. It was selected because its listed purpose is specifically lens rewetting and comfort. Limitation: These drops do not replace the multipurpose solution used to clean and disinfect lenses. Check the product directions and confirm suitability for your lens type.
Biotrue Hydration Plus Solution

Biotrue Hydration Plus is a multipurpose solution that cleans and disinfects lenses, removes dirt, and dissolves protein buildup. The product information describes up to 20 hours of moisture based on a laboratory study, and reports more moisture retention for 12 hours compared with original Biotrue Multi-Purpose Solution in a laboratory study. A lens case is included.
Best for: Wearers looking for one solution for lens cleaning, disinfection, and conditioning. It stands out among these options for its stated hydration focus. Limitation: The stated moisture duration comes from laboratory testing, so it should not be treated as a guarantee of comfort for every wearer.
Boston Rewetting Drops For RGP Lenses

Boston Rewetting Drops are formulated for rigid gas permeable (RGP) lenses. The listed uses include scleral and ortho-k lenses, as well as other RGP lenses. The drops coat, lubricate, and rewet the lens while it is being worn; the product information also says they can help remove particles and debris.
Best for: People wearing RGP lenses who need a lens-specific rewetting drop. It was selected because it clearly identifies rigid lenses as its intended use. Limitation: The product is not described as a general soft-contact-lens drop. Choose it only when its directions match your lens type.
UpaClaire Ultrasonic Lens Cleaner

This USB-C rechargeable device uses 23,000 Hz ultrasonic energy, according to its product description. The listed features say it is intended for several lens types and is used with contact lens solution. The seller describes it as helping remove protein, calcium, lipid, and other deposits, and says the combination with solution can improve cleaning effectiveness.
Best for: Lens wearers considering an additional cleaning tool rather than drops for immediate dryness. Limitation: The product information does not establish that the device replaces the cleaning and disinfection steps required by your lens-care instructions. Confirm its suitability with an eye-care professional and follow the lens and solution directions.
OPTI-FREE Replenish Solution

OPTI-FREE Replenish is a multipurpose contact lens solution with cleaning and disinfecting features. Its TearGlyde reconditioning system is described as working with tears to create a shield of comfortable moisture. The product information also says its formula targets microorganisms that can cause eye infections.
Best for: Wearers who want a multipurpose solution that pairs lens care with a stated moisture-conditioning feature. Limitation: It is a lens-care solution, not a rewetting drop for use in the eye. The listed directions warn against storing lenses or rinsing the case with water or a non-sterile solution.
Buying Guide: How To Choose Contact Lens Comfort Products
Do you need rewetting drops or a multipurpose solution?
Rewetting drops are intended to add moisture to lenses while they are worn, subject to the product’s directions. Multipurpose solutions are used for lens-care steps such as cleaning, rinsing, and disinfecting. They are not interchangeable. For dryness during wear, compare Refresh Contacts with Boston Rewetting Drops, but first check which lens types each product supports.
Which product fits your lens type?
Boston Rewetting Drops specifically identify RGP, scleral, and ortho-k lenses. Refresh Contacts is presented as a contact lens rewetting drop, but buyers should still check its labeling for their lens type. For solution or device compatibility, use the lens manufacturer’s care instructions and ask an eye-care professional when uncertain.
How should you compare multipurpose solutions?
Biotrue Hydration Plus emphasizes moisture retention and includes a lens case. OPTI-FREE Replenish highlights cleaning, disinfection, and its TearGlyde moisture-conditioning system. Choose based on the care routine recommended for your lenses, not solely on comfort claims. Follow the stated soak and handling directions, and never substitute tap water for sterile lens-care products.
When might a cleaning device make sense?
An ultrasonic cleaner may appeal to someone looking for an additional cleaning method. However, the listed device is described for use with contact lens solution; do not assume it replaces disinfection or any step prescribed for your lenses. Confirm device compatibility and keep the regular care routine recommended by your eye-care professional.
Frequently Asked Questions
Which listed product is best for contact lens dryness?
Refresh Contacts is the clearest general choice in this list for rewetting lenses. Boston Rewetting Drops are the lens-specific option for RGP wearers. Check the package directions before use.
Can multipurpose solution be used as rewetting drops?
These products are listed as lens-care solutions, not drops for use in the eye. Use only products labeled for application while lenses are worn.
Are Boston Rewetting Drops for soft lenses?
The listed product information specifies rigid gas permeable lenses, including scleral and ortho-k lenses. It does not identify soft lenses as an intended use.
Does an ultrasonic cleaner replace lens solution?
The UpaClaire description says to use the device with contact lens solution. Do not treat it as a replacement for the cleaning and disinfection routine specified for your lenses.
What should I do if contacts stay uncomfortable?
Persistent discomfort, redness, or vision changes warrant removing the lenses and contacting an eye-care professional. A comfort product may not address the cause.